Albuterol is a drug that is normally given to people with asthma to help them breathe better. Research has found that in the form of a long acting pill, it also has the effect of increasing lean muscle mass in normal individuals.

There's pretty compelling evidence that shows albuterol is just about as effective as clenbuterol at increasing anabolism, with one exception: Albuterol is effective at "clinically safe" doses (in man), and clenbuterol is not. In other words, in order to achieve an anabolic effect from clenbuterol, you need to exceed its safety limits (which is not necessarily dangerous or undesirable for us healthy bodybuilder types).

On the other hand, albuterol, at clinically safe doses, increases whole-body protein content in rats by 20% in just three weeks! So it really does increase protein synthesis. Furthermore, there are several studies that show albuterol is effective at significantly increasing power output and muscular endurance in man. Additionally, albuterol is heart healthy, prevents muscle catabolism, and is a pretty darn good asthma medicine to boot. By all indications, albuterol should be effective for at least three to four weeks at increasing muscle mass before you need a week off from use. And from a personal experience, this bears out as well. I've had reasonably good success with albuterol, and I suggest anyone who has access to the drug to give it a try. I recommend 16 mg a day, taken in either two doses spaced 8-10 hours apart, or four doses spaced about four hours apart. Go on cycles of 3-4 weeks on, one week off. Be careful about stacking other adrenergic agonists, like ephedra, with albuterol. If you can tolerate the combination, go for it, but test it out first. The half-life of albuterol is about five hours, so if the doses are too frequent, there's a cumulative effect that could get the better of you, sending your heart into an arrhythmia that rivals the tempo of a hummingbird's wings. Just be aware that there are enormous tolerance differences between people. So start out slowly with minimal doses until you get a handle on how your body reacts to these compounds. And regarding aspirin, bag the idea of using it for anything other than pain control. Stacking it with stimulants is out of date and actually counterproductive.

Medical Abstract

BACKGROUND: In animals and healthy volunteers beta2-adrenergic agonists increase muscle strength and mass, in particular when combined with strength training. In patients with facioscapulohumeral muscular dystrophy (FSHD) albuterol may exert anabolic effects. The authors evaluated the effect of strength training and albuterol on muscle strength and volume in FSHD. METHODS: Sixty-five patients were randomized to strength training of elbow flexors and ankle dorsiflexors or non-training. After 26 weeks albuterol (sustained-release, 8 mg BID) was added in a randomized, double-blind, placebo-controlled design. Primary outcome was maximum voluntary isometric strength (MVIC) at 52 weeks. Secondary outcomes comprised dynamic strength and muscle volume. RESULTS: Training and albuterol were well tolerated. Training of elbow flexors did not result in a significant effect on MVIC, but dynamic strength improved significantly. Elbow flexor MVIC strength increased significantly in albuterol vs placebo treated patients. Ankle dorsiflexor strength decreased in all groups. Eleven out of twelve non-trained muscles in the albuterol group showed a positive effect on MVIC compared to the placebo group (p < 0.05 in seven muscle groups). Muscle volume decreased in the placebo-treated, and increased in the albuterol-treated patients. No synergistic or antagonistic effects were observed between training and albuterol. CONCLUSIONS: In FSHD strength training and albuterol appear safe interventions with limited positive effect on muscle strength and volume. Consequences of prolonged use are presently unclear, which precludes routine prescription.

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